http://www.ncbi.nlm.nih.gov/cgi-bin/Entrez/framik?db=G&gi=115


Summary sequence view BLAST Pubmed Nucleotide Protein Genome Structure Popset Taxonomy Help Escherichia_coli K12, complete genome Microbial genomes Refseq: NC_000913 Genbank: U00096 Total Bases: 4639221 bp Completed: Oct 15,2001. Feature table: Protein coding genes: 4279 Structural RNAS: 115 BLAST protein homologs: COGS (Clusters of Orthologous Groups) 3d Structure (Sequences with known structure) Taxmap (Sequences grouped by superkingdom) Taxplot (3-way genome comparison) CDD (Conserved Domain Database) Contributor: U Wisc See genome at U Wisc Download chromosome sequence data from NCBI FTP site BLAST your query sequence against the genome BLAST against protein sequences Start from: Search for gene Protein coding genes distribution map To see map locations of genes, click on a region in the map, to zoom_in on_that region Gene Classification based_on COG functional categories Organism: Escherichia_coli K12 Genetic Code: 11 Lineage: Bacteria; Proteobacteria; gamma subdivision; Enterobacteriaceae; Escherichia. The complete genome sequence of Escherichia_coli K-12 Blattner, F. R.,Plunkett, G. III, Bloch, C_a.,Perna , N_t.,Burland, V.,Riley, M.,Collado-Vides, J.,Glasner, J. D.,Rode, C . K.,Mayhew, G. F.,Gregor, J.,Davis, N_w.,Kirkpatrick, H. A.,Goeden , M. A.,Rose, D. J.,Mau, B. and Shao, Y. Science 277 (5331), 1453-1474 (1997) 97426617 Direct Submission Blattner, F. R. Submitted (16-JAN-1997) Guy Plunkett III, Laboratory of Genetics, University of Wisconsin, 445 Henry Mall, Madison , WI 53706, USA. Email: ecoli@genetics. wisc. edu Phone: 608-262-2534 Fax: 608-263-7459 Direct Submission Blattner, F. R. Submitted (02-SEP-1997) Guy Plunkett III, Laboratory of Genetics, University of Wisconsin, 445 Henry Mall, Madison, WI 53706, USA. Email: ecoli@genetics. wisc. edu Phone: 608-262-2534 Fax: 608-263-7459 Direct Submission NCBI Microbial Genomes Annotation Project. Submitted (26-SEP-2001) National Center for Biotechnology Information, NIH, Bethesda , MD 20894, USA COMMENT PROVISIONAL REFSEQ: This record has not_yet been subject_to final NCBI review. The reference sequence was_derived from U00096. This sequence was_determined by the E_coli Genome Project at the University of Wisconsin-Madison (Frederick R. Blattner, director. Supported by NIH grants HG00301 and HG01428 (from the Human Genome Project and NCHGR. The entire sequence was_determined independently from E_coli K-12 strain MG1655. Predicted open reading frames were_determined using Genemark software, kindly supplied by Mark Borodovsky, Georgia Institute_of_technology, Atlanta, GA, 30332 e-mail: mark@amber. gatech. edu. Open reading frames that have_been_correlated with genetic loci are being_annotated with CG Site Nos. unique ID nos. for the genes in the E_coli Genetic Stock Center (CGSC) database at Yale_university, kindly supplied by Mary Berlyn. A public version of the database is accessible (http://cgsc. biology. yale. edu. Annotation of the genome is an ongoing task whose goal is to make the genome sequence more useful by correlating it with other data. Comments to the authors are_appreciated. Updated information will_be available at the E_coli Genome Project's World_wide_web site (http://www. genetics. wisc. edu.*****The E_coli K-12 sequence and its annotations are_updated periodically; this_is version M54. No sequence changes. Annotation updates: updated gene identifications and products; all new functional assignments courtesy of Monica Riley; added promoters, protein binding sites, and repeated sequences described in reference 1. The unique numeric identifiers beginning with a lowercase'b'assigned to each gene (protein -or RNA-encoding) are_designated now as gene synonyms instead_of labels. This should allow them to be_searched for in Entrez as gene names. COMPLETENESS: full length. Comments and suggestions to: info@ncbi. nlm. nih. gov


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