http://www.ncbi.nlm.nih.gov/genome/guide/HsChr8.shtml
Human Chr 8 Pubmed Entrez BLAST OMIM Taxonomy Structure Search Genbank Genemap'99 Locuslink MEDLINE OMIM Unigene Maps dbsts for Human Genome Resources Select a Chromosome: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 X Y Mapviewer Chr 8 Locuslink Chr. 8 Loci Unigene Chr. 8 Clusters Mouse Homologies for Human Chr. 8 Chromosome 8 Genes on Chromosome 8 Lipoprotein_lipase: Human lipoprotein_lipase (LPL) is an important enzyme in lipid metabolism. It is_thought to possibly have a role in obesity and atherosclerosis. There_are a number of polymorphisms found in the LPL gene which will allow investigators to address the role of LPL in these areas. LPL in the SNP Database Some diseases associated with chromosome 8 mutations Cohen Syndrome Langer-giedion_syndrome Nijmegen Breakage Syndrome Werner_syndrome See OMIM or Genes and Disease for additional examples and detailed information. OMIM Home_page OMIM Morbid Map Genes and Disease Sequencing Progress Euchromatic size: 155000 kb Finished sequence: 97537 kb Percent finished: 62.9%Number of contigs: 234 List contigs by size List contigs by position Sequencing is being coordinated by Washington University and The Whitehead Institute. Major contributions have come from: JFCR Jena, Germany Washington University STS Maps Map STSS Type Ref Genemap '99 1206 RH 1 Whitehead 739 YAC 2 Stanford 446 RH 3 Genethon 249 Link 4 Cytogenetics Mitelman et_al. 5) have_cataloged recurrent chromosome aberrations associated with cancers. Chromosome 8 aberrations References 1 Deloukas et_al. 1998). ) A physical map of 30,000 human genes. Science 282,744-746.2 Hudson et_al. 1995). ) An STS-based map of the human genome. Science 270,1945-1954.3 Stewart et_al. 1997). ) An STS-based radiation hybrid map of the human genome. Genome Res 7, 422-433.4 Dib, et_al. 1995). ) A comprehensive genetic map of the human genome based_on 5, 264 microsatellites. Nature 380,152-154.5 Mitelman, et_al. 1997). ) A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nat Genet Apr 15 Suppl. 417-474. Comments or Questions? Write to the NCBI Service Desk